Loss of PPARα perpetuates sex differences in stroke reflected by peripheral immune mechanisms
نویسندگان
چکیده
منابع مشابه
Sex differences in stroke.
Increasing evidence suggests that sex differences exist in the etiology, presentation, treatment, and outcome from stroke. The reasons for these sex disparities are becoming increasingly explored, but large gaps still exist in our knowledge. Experimental studies over the past several years have demonstrated intrinsic sex differences both in vivo and in animal models which may have relevance to ...
متن کاملSex Differences in Stroke Recovery
INTRODUCTION This study examined differences between men and women in the ability to perform basic activities of daily living, instrumental activities of daily living, and higher physical functioning after stroke. The objective of the study was to determine whether sex differences in stroke recovery can be explained by depressive status beyond older age, stroke severity, prestroke physical func...
متن کاملSex differences in peripheral vascular adrenergic receptors.
Although the incidence of many vascular diseases differs in men and women, sex differences in vascular physiology have not been extensively examined in human in vivo studies. The present study compared finger blood flow responses of normal men and women with brachial artery infusions of adrenergic agonists and with other neurally and nonneurally mediated procedures. In response to phenylephrine...
متن کاملSex differences in caspase activation after stroke.
BACKGROUND AND PURPOSE Over the past 5 years, experimental data have emerged that ischemia-induced cell death pathways may differ in males and females. Cell death in males is triggered by poly(ADP-ribose) polymerase activation and nuclear translocation of apoptosis-inducing factor. We have previously shown that interference with this pathway benefits males but not females after an experimental ...
متن کاملSex differences in first-ever acute stroke.
BACKGROUND AND PURPOSE There are few studies analyzing stroke in women, taking into account the vascular risk factors, cause of stroke, clinical picture, and outcome. The purpose of this study was to analyze possible sex differences in patients suffering first-ever acute stroke. METHODS From December 1995 to January 2002, 1581 patients with first-ever acute stroke were analyzed, taking into a...
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ژورنال
عنوان ژورنال: Metabolic Brain Disease
سال: 2016
ISSN: 0885-7490,1573-7365
DOI: 10.1007/s11011-016-9805-2